X-ray Crystallography; Understanding of the
Structures of Biomedically Relevant Molecules (e.g.
carbohydrates and their derivatives, small peptides, and
potential antiviral agents); Studies of the Solid-state
Structures of Benzylideneanilines, Benzylideneazines, and
Selected Fluorinated Compounds; Solid-state Study of Strict
Isosteres (chemically different molecules having
virtually identical space-filling requirements).
The projects highlighted below involve the synthesis,
crystallization, and characterization of compounds of
interest; in addition, crystal structures of selected
compounds are determined through the assistance of the
X-ray Crystallographic Laboratory (XCL) of the University
of Minnesota. Data sets collected at the XCL are
transmitted to the Organic Solid-State Research
Laboratory in the University of St. Thomas Chemistry
Department, where students are given the opportunity to
solve and refine the crystal structures through the use
of the SHELXTL software package. Research students in
this UST laboratory are also given access to the
Cambridge Crystallographic Database.