Solving Structures by NMR
1. Find the pieces or structure fragments
Common Fragments - CH3, CH2, CH
Use Integration to tell you:
CH3, CH2, CH
Number of substituents on an aromatic ring
e.g. if the integral is 4 it is disubstituted
Use Chemical Shift to tell you
Presence of functional groups and which fragment it is connected to
Use spin-spin splitting
to tell you connectivity
Make sure it fits the molecular formula
Assign each peak in the spectrum